SELENIUM
General Description:
- Se is a part of the detoxifying enzyme, phospholipid hydroperoxide glutathione peroxidase,
which destroys damaging free radicals called hydroperoxides and detoxifies peroxidized
fats (lipid peroxides) within the membrane, thereby sparing vitamin E
- works in synergy with vitamin E as a powerful antioxidant
- Se as L-selenomethionine is better absorbed than sodium selenite
Actions:
- helps to maintain the health of muscle, RBCs, and keratins
- supports the pancreas and the immune system
- helps decrease the toxicity of mercury, silver, and cadmium, which are harmful when
they accumulate in the body
- as an antioxidant it shows cancer-fighting potential, but ironically it was once thought
to be cancer causing
- studies show that cancer death rates decrease as the average blood level of selenium
increases (27 countries showed this ''inverse relationship'')
- lowest levels of cancer have been found among people living where the soil is selenium-rich,
with evidence strongest for cancers of the digestive tract, probably because they are the
organs most likely to come in contact with Se
Deficiency:
- Se deficiency almost certainly does not cause cancer directly but low Se intakes probably
lower our defenses against substances that do
- on a low-selenium diet, sufficient amounts of the key selenium-containing enzyme, glutathione
peroxidase, may be lacking, depriving us of this important substance that fights free radicals
- Se deficiency is often assessed in medicine by the level of glutathione peroxidase activity
Interactions and Toxicity:
- most nutritionists exaggerate the amount of Se likely to be toxic
- Se toxicity is termed selenosis
- symptoms of toxicity include: bad teeth, brittle fingernails, discolored skin, dizziness,
fatigue and tiredness, garlic odor on breath, GI complaints, hair brittleness and/or loss
possibly in bunches, irritability, jaundice, and skin inflammation
- reports of an unusual rate of spontaneous abortions ''miscarriages'' among women working
with sodium selenite powder
Sources:
- whole grains, if grown in selenium-rich soil
- mushrooms and radishes, followed by carrots and cabbage, have the highest levels of
Se for vegetables, if grown in Se-rich soil
- most fruits are low in Se