THIAMIN (Vitamin B1):
General Description:
- thiamin is a water-soluble vitamin that has several different roles in the body
- however, the fat-soluble forms, called allithiamins, are superior to the water.soluble
forms
Actions:
- helps your body release energy from food - specifically carbohydrates.
- required for the oxidative decarboxylation of alpha-keto acids and for the transketolase
activity in the pentose phosphate pathway (ie carbohydrate burning)
- keeps appetite, digestive tract, and the nervous system healthy
- anti-beriberi, anti-neuritic, and anti-aging vitamin
- essential for proper protein metabolism
- promotes growth
- protects the heart muscle
- stimulates brain action
- improves peristalsis and helps prevent constipation
- helps maintain normal RBC count
- protects against the damaging effects of lead poisoning
- prevents edema, or fluid retention, in connection with heart condition
- improves circulation
- prevents fatigue and increases stamina
Deficiency:
- the body can only absorb and retain so much thiamin at a time and thus it must be consumed
everyday
- except those afflicted with alcoholism, genetic disease, or metabolic disorders thiamin
intake is usually adequate.
- symptoms of thiamin deficiency: tired and lacking energy, irritability, depression,
anger, loss of appetite and weight, headaches, indigestion (defective HCl production),
diabetes, neuritis, edema, and constipation.
- hallmark of deficiency is nerve damage of the legs.
- final stage of thiamin deficiency is beri-beri which is very painful and can lead to
death if left untreated.
- there are two types of beri-beri - ''dry'' and ''wet''
- in ''wet'' the body retains too much fluid and there is abnormal heart functioning
- in ''dry'' there are nerve and muscle problems
- heart and digestive malfunctioning can usually be reversed, however, nerve malfunctioning
may be more difficult to correct.
- antacids can innactivate thiamin
- diuretics or ''water pills'' are known to increase thiamin excretion
- barbiturates can decrease absorption of thiamin
Interactions and Toxicity:
- high doses of thiamin may enhance drugs known as neuromuscular blocking agents.
Sources:
- whole grains are the best source
- brewer's yeast, wheat germ and bran, rice polishings, all seeds and nuts, beans especially
soybeans, milk and milk products, beets, potatoes, and green leafy vegetables