VITAMIN E
General Description:
- fat-soluble vitamin
- main function is as an antioxidant
- the correct units for vitamin E are milligrams of alpha-tocopherol equivalents (alpha
TE)
- dl-alpha-tocopherol is a synthetic form of vitamin E
- d-alpha-tocopherol is the natural form which has been shown to raise serum vitamin E
levels 40% higher and the RBC levels 300% higher than the synthetic form
Actions:
- promising substance in the treatment and prevention of cancer and in the treatment of
PMS
- helps prevent blood clots
- plays a role in the metabolism of polyunsaturated fats, the kind that help lower blood
cholesterol and prevent heart disease
- acts as an antioxidant preventing certain harmless chemicals in the body from becoming
harmful ones
- an antioxidant also prevents a benign substance from being oxidized into a harmful one
that contributes to the cancer process
- vitamin E may benefit those with benign breast lumps and PMS
- glutathione protects cells by surface cell membranes whereas vitamin E is located inside
cell membranes, where the lipid peroxidation occurs
- vitamin E breaks the reaction by absorbing the free radicals to form tocopherol and
tocopheroxyl radicals
- breaking the chain quickly uses up vitamin E stores
- however, vitamin C neutralizes tocopheroxyl free radicals and regenerates vitamin E
again
- Se helps both glutathione and vitamin E, as it forms what is called the active site
where glutathione destroys peroxide radicals
- the vitamin E content of lymphocytes and neutrophils is 10-20 times that of RBCs indicating
its importance to the immune system
- vitamin E also reduces the damage caused by the immune system itself
- oxygenates the tissues and reduces the need for oxygen intake
- effective as a vasodilator
- prevents scar tissue formation
- effective antithrombin and a natural anti-coagulant
- essential for healthy function of reproductive glands
- good for: heart disease, asthma, phlebitis, arthritis, burns, angina, emphysema, leg
ulcers, restless legs, varicose veins, hypoglycemia etc.
- improves glycogen storage in the muscles
- used successfully in prevention and treatment of reproductive disorders, miscarriages,
male and female infertility, still births, and menopausal and menstrual disorders
Deficiency:
- total vitamin E intake from food is unlikely to exceed 20 IU/day
- the requirement for vitamin E for an individual depends on the levels of fatty acids
in his tissue that can suffer oxidation, and the levels of free radicals he generates
- deficiency reduces bodily levels of zinc because the two nutrients interact to protect
the membranes against damage by free radicals (lipid peroxidation)
- when there is not sufficient vitamin E, the body compromises by using more zinc, and
this can deplete zinc stores and thus increase bodily copper levels
- symptoms: cardiovascular disease, may cause degeneration of the epithelial and germinal
cells of the testicles and lead to loss of sexual potency
- prolonged deficiency may cause reproductive disorders, abortions, miscarriges, male
or female sterility, muscular disorders and increased fragility of RBCs
Interactions and Toxicity:
- vitamin E prolongs the amount of time required for necessary clotting of the blood which
can lead to internal bleeding
- vitamin E, when initially taken in large doses, improves the tone of the heart muscle,
and could lead to an increase in blood pressure in susceptible individuals
- excess EFAs can deplete the body of vitamin E
- known antagonists of vitamin E: inorganic iron, estrogenic drugs, chlorine or chlorinated
water
Sources:
- unrefined cold-pressed, crude vegetable oils especially wheat germ and soybean oil
- all whole raw or sprouted seeds, nuts, and grains
- green-leafy vegetables and eggs
- wheat germ must be less than 1 week old unless frozen